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KMID : 1022820190100020032
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Journal of Multiple Sclerosis and Neuroimmunology
2019 Volume.10 No. 2 p.32 ~ p.35
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Case Reports of Clinical Variability in Myelin Oligodendrocyte Glycoprotein (MOG ) Encephalom yelitis Patients
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Kim Sung-Hyun
Kwack Dong-Won
Oh Jee-Young
Choi Kyo-Min
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Abstract
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Most experts now consider myelin oligodendrocyte glycoprotein (MOG) antibody positive encepha- lomyelitis as a disease entity immunopathogenetically distinct from multiple sclerosis and neuro- myelitis optica spectrum disorder (NMOSD). MOG-encephalomyelitis patients usually present with recurrent optic neuritis or limb paralysis due to myelitis, but also behavioral change, seizures, or en- cephalopathies are often the first manifestations in these patients. Herein, we report two cases of MOG-antibody encephalomyelitis who presented with atypical symptoms that included aggressive behavior, multiple cranial neuropathies, and seizures.
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KEYWORD
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Myelin-oligodendrocyte glycoprotein, Encephalomyelitis, Magnetic resonance imaging
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